Chelsea have been drawn against lower league opposition for the third round in a row in the Quarter Finals of the League Cup.
The Premier League leaders will have to travel to Derby County in the next stage as they attempt to win the competition for the first time since 2007.
Elsewhere Liverpool will have to overcome Bournemouth at the Goldsands Arena in a repeat of a fourth round tie in the FA Cup earlier this year.
Liverpool won 0-2 in Bournemouth on that occasion thanks to goals from Victor Moses and Daniel Sturridge.
Draw in Full:
Derby County vs Chelsea
Bournemouth vs Liverpool
Sheffield United vs Southampton
Tottenham vs Newcastle
Ties are due to be played during the week commencing 15 December.